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When temperaments can fluctuate from energetic and excitable, to extremely sluggish and indifferent, you might look up this remedy. Its many symptom options include nervous fatigue, occasional sleeplessness, headaches, low back pain, sweating fever, stomach distress from smoking, ‘ball in the anus’ constipation and urinary applications. In women, Sepia relieves symptoms related to: minor vaginal irritation (dryness, thrush), menopause, heavy periods with a ‘bearing down sensation’, hot flashes and PMS, etc., especially if marked by irritability and indifference. Sepia can help both sexes with ‘never well since puberty’ complaints.